Woodson Research Center, Rice University

Guide to the Frederick Rudolph biochemistry academic papers, 1969-2002 MS 409

creator Rudolph, Frederick B.
Title: Frederick Rudolph biochemistry academic papers
Dates: 1969-2002
Identification: MS 409
Quantity: 35 Linear Feet(35 boxes)
Language: English
Repository: Woodson Research Center, Rice University, Houston, Texas

Biographical / Historical

Frederick B. Rudolph was a ground-breaking researcher and a devoted educator in biochemistry who was hired to teach at Rice University in 1972. He died in the midst of his customary activities at the university in 2003 at the age of 58.

Fred Rudolph’s most far-reaching research concerned the enzyme adenosine desminase. It was reported in the June 2, 1991 issue of the journal Science. Working with two colleagues, Rudolph found that an immune deficiency occurred when this enzyme, normally present in all body cells, was missing from B and T lymphocytes, cells of the immune system located in the blood, spleen, and thymus. One important outcome of this discovery is that it led every major producer of infant formula worldwide to add what the work showed is necessary for development of a strong immune system.

As an educator, Fred Rudolph was not only an effective teacher of his own courses, but also a leader in curriculum development nationally. For multiple years he was involved as a workshop leader in Project Kaleidoscope, an informal national alliance of individual institutions and organizations committed to strengthening undergraduate science, mathematics, engineering, and technology education.

He was also a participant in numerous inter-institutional activities with the Texas Medical Center, among them the Rice-Baylor College of Medicine Planning Committee, which sponsored a pathway for qualified students to be admitted to Baylor College of Medicine after successful completion of a specified sequence of Rice courses.

Rudolph’s efforts as an educator also reached out to pre-college-age young people. He established short summer residential programs offered at Rice to students in economically disadvantaged schools, both in Houston and in the Rio Grande Valley. The aim of these programs was to expose young people to the activity of laboratory research and to career possibilities in science and medicine.

In addition to work in his academic discipline, Rudolph made important contributions to the institutional life of Rice. He was a member and then chair of the Admissions and Financial Aid Committee for more than two decades.

Scope and Contents

The papers of biochemist and cell biologist Frederick (Fred) Rudolph (1944-2003) document his 31 years on the faculty of Rice University and his tenure as director of Rice's Institute of Biosciences and Bioengineering. Topics include Rudolph's research, grant projects, patents, courses taught, departmental administration, and committee service. Formats include reports, notes, charts, correspondence, slides, and photographs. Rudolph's work led to the discovery that several key nucleotides needed by infants for healthy immune function were missing from standard baby formula, leading every major producer of baby formula to add those ingredients.


Conditions Governing Access

This material is open for research.

Conditions Governing Use

Permission to publish from this material must be facilitated through the Woodson Research Center, Fondren Library, Rice University.

Index Terms

Subjects (Persons)
Rudolph, Frederick B.
Rudolph, Frederick B.
Subjects (Organizations)
Rice University
slides (photographs)
manuals (instructional materials)
compact discs
letters (correspondence)

Administrative Information

Preferred Citation

Frederick Rudolph biochemistry academic papers, 1969-2002, MS 409, Woodson Research Center, Fondren Library, Rice University.

Immediate Source of Acquisition

Transfered by University Historian, Melissa Kean, April 20, 2004.

Processing Information

This material has been sorted into series groups, but has not been arranged into order with the series, and has not been fully refoldered.

Detailed Description of the Collection

1-8 Series I: Research 1980-2002
Scope and Contents
Notes, lab charts, copies of published articles, correspondence.

8-18 Series II: Grants 1980-2003
Scope and Contents
Applications, reports, budget information, correspondence for grants in which Dr. Rudolph was involved either as Principle Investigator or some other capacity. Funding agencies include National Institute of Health, DuPont, Welch Foundation, National Science Foundation, Eisenhower, Environmental Protection Agency, Department of Energy, Glaxo, and the Howard Hughes Medical Institute.

19-20 Series III: Patents 1980-1999
Scope and Contents
Correspondence and research.

21-29 Series IV: Teaching at Rice
Scope and Contents
Course syllabi and evaluations, student work, correspondence, departmental administrative files, including the regular business and renovation of Keck Hall (Chemistry) on the Rice campus. Includes files on the national Kaleidoscope educational project.

30-31 Series V: Committees
Scope and Contents
Rice University committees and other regional or national committees on which Rudolph served, generally relating to education.

32-34 Series VI: Videos, photographs, and computer disks
Scope and Contents
Most appear to have been used for classroom purposes.

35 Series VII: Personal effects
Scope and Contents
Items from Rudolph's desk, including rolodex, campus parking pass, and more.